Because enzymes connect to their substrate through a lock-and-key system, where the shape of the substrate and the enzyme has to fit like puzzle pieces. Then only the enzymatic reaction can occur.
The correct answer is that Matt will be more prone to infections.
The recommended dietary allows differs with age, sex, and health status. Leen is an healthy female adult so the RDA should be 15 mg so if she has consumed 6 mg the percentage is 6/15*100 = 40%