Question

Scientists have modified a clathrin molecule so that it still assembles but forms an open-ended lattice instead of a closed spherical cage. How would this clathrin molecule affect endocytosis in cells?
A. Vesicles would be larger, increasing the cargo endocytosed.
B. All movement of molecules into and out of the cell would cease.
C. Vesicles cannot form properly without a clathrin cage, thus inhibiting endocytosis.
D. Endocytosis would be un-affected, since adaptors and receptors can still interact.

Answer 1

Answer:

C. Vesicles cannot form properly without a clathrin cage, thus inhibiting endocytosis

Explanation:

Endocytosis is the process by which substances are brought into the cell.

Clarithrin mediated endocytosis or receptor mediated is the process where metabolites are absorbed through formation of vesicles that will contain the absorbed substances.

Clarithrin proteins are responsible for the formation of these vesicles which are closed spherical cages.

Formation of open ended lattice will inhibit endocytosis due to improperly formed vesicles.