A need for an established government in order to maintain peace. A government is able to implement laws and taxes.
It was the anti-westward movment forbidding all settlers to cross the appalachian mountains.
Duct Tape.
Remember the Dept of Homeland Security warning to purchase duct tape and plastic to help against biological or chemical attacks. And yes, NASA does send up duct tape with every flight. It was useful in the famous troubled Apollo 13 mission, and was credited in part with saving the lives of those astronauts.
They killed soldiers, attacked and destroyed wagon trails
With the rise of colonies in the Americas and their need to incorporate laborers, Europeans focused their attention to Africa, and some asserted that the Transatlantic Slave Trade would make it possible for Africans to make contact with Christianity and 'civilisation'.
For this reason, religion was an important driver during slavery period, since Africans slaves, after their arrival to the Americas, were subject to different methods to make them more docile, being Christianity a crucial part.