<span>A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?
</span><span>B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
</span>
Imatinib works against CML by binding close to the ATP binding site of bcr-abl. The binding results to the<span> locking in of the bcr-abl to a closed or self-inhibited conformation and inhibiting the enzyme activity of the protein </span><span>semi-competitively.</span>
Women have XX chromosomes and Men have XY
BLANK 1: Male
BLANK 2: Female
Answer:
A. three pounds
Explanation:
it definitely doesn't weigh ounces :)
Answer:
Option B, ionic bonds; salt
Explanation:
All medicines either in the form of pills or liquid interact with our body by forming a bond with target specific receptors. For instance if a pain killer is taken then it shall form bond with receptors produced by pain and inflammation
So medicines are basically chemical which interact with biomolecules such as enzymes, nucleic acid, hormones, ions etc. by forming ionic bond, hydrogen bond, van der wall force etc. in the active site of enzyme.
These salt molecule remain stable in normal conditions but as they come in contact with digestive system of the body (with different pH) they release the drugs
Hence, option B is correct
