Enveloped viral membranes are generally (C)lipid bilayers with associated virus-specific (C)glycoproteins.
Viruses are intracellular parasites that hijack the cellular machinery for their own replication. Therefore, an essential step in the viral life cycle is the transfer of the viral genome into cells. Enveloped viruses (viruses with a lipid envelope) use a two-step process to release their genetic material into the cell.
It first binds to specific surface receptors on target cell membranes and then fuses with these. Viruses and cell membranes. This last step can occur at the cell surface or after internalization of the virus particle by endocytosis or another pathway (such as micropinocytosis).
Strikingly, the virus-cell-membrane fusion process proceeds along essentially the same intermediate steps as other membrane fusions that occur, for example, in vesicle fusion at neural synapses or cell-cell fusion in yeast mating. Fusogens, special viral proteins, facilitate the fusion of viruses and cell membranes.
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