Firstly, the enzyme, DNA Helicase breaks the Hydrogen bonds between a specific region of the DNA molecule and unwinds the duplex DNA molecule at the targeted gene sequence site.
Then, RNA Polymerase binds at the 3` site of the gene sequence of the sense/coding strand(only one strand) that acts as the template for mRNA synthesis. RNA Polymerase then matches free nucleotides by complementary base-pairing(A-U & C=G), working in the 5`to3` direction. Hydrogen bonds then form between the complementary bases, holding the nucleotides in place. Each free adjacent nucleotide is joined at 3` ends by Condensation reactions with the other to form Phosphodiester bonds.
Once the mRNA molecule is formed, it is separated from the synthesis complex and leaves the nucleus through pores in the nuclear envelope to moves towards ribosomes for Translation.
Lastly, the DNA double helix rewinds by forming Hydrogen Bonds.
Answer:
Each molecule of DNA is a double helix formed from two complementary strands of nucleotides held together by hydrogen bonds between G-C and A-T base pairs. Duplication of the genetic information occurs by the use of one DNA strand as a template for formation of a complementary strand.
Explanation:
Socially isolated children are at increased risk of health problems in adulthood. Lack of social relationships negatively impacts the development of the brain's structure. It causes loneliness and high levels of stress. A person is at higher risk of developing cardiovascular disease, elevated blood pressure, infectious illness, cognitive deterioration, and mortality.
Sickle cell trait is apparently an adaptation for the prevention of Malaria. Sickle cell trait is a condition in which the red blood cells are abnormally shaped, if they inherit two faulty copies of the gene for the oxygen-carrying protein hemoglobin. The faulty gene persists because even carrying one copy of it confers some resistance to malaria. As a result, the frequencies of sickle cell carriers are high in malaria endemic areas.