The substrate and the active site both need to fit together perfectly in order for the enzyme to work properly. If their shape is changed, typically through heat or a change in pH, the enzyme will not work.
Answer:
<u>Liquefaction</u> refers to the tendency of a foundation material (such as soil) that is water-logged to lose its internal cohesion and mechanically fail to provide support during earthquake shaking.
Explanation:
Liquefaction occurs when an unbound material (usually sand), which is saturated in water, loses its resistance to shear due to intense and rapid vibration (earthquake), which breaks its granular structure by reducing its inter-granular pressure and flow like a liquid because of an increase in pressure.
Liquefaction usually manifests itself in loose, saturated and non-cohesive soils, formed by young deposits of sands and sediments of similar particle sizes. If the soil is dense there will be less chances of liquefaction. Older deposits, in general, are more dense and cohesive. At higher density, more interstitial pressure is needed for liquefaction to occur.
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