The statements that are true are the following:
1. The levels of microsomal enzymes are decreased.
Microsomal enzymes are functional parts of the human liver, which participate actively in the drug metabolism. It has been shown that the activity of these enzymes is lower in children, reaching its full activity in adult individuals.
2. First pass elimination is reduced because of the immaturity of the liver.
First pass elimination is a phenomenon of drug metabolism, that occurs in the liver or the gut and involves the reduction of the drug concentration before it reaches the systemic circulation. In neonates, the liver is immature and undergoes several changes during the postnatal period.
3. Gastric emptying is slowed because of slow or irregular peristalsis.
Peristalsis is a term referring to the movement of food to several positions of the digestive tract, through muscle contractions. Gastric emptying is strongly affected by peristalsis. Some children have irregular peristaltic movement.
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There are three types of muscle tissue<span>: Visceral, </span>cardiac<span>, and </span>skeletal<span>. </span>Visceral Muscle<span>. </span>Visceral muscle<span> is found inside of organs like the </span>stomach<span>, intestines, and </span>blood vessels. The major types of muscle systems are the skeletal muscles, cardiac muscles and smooth muscles.<span> The skeletal muscles are voluntary muscles, whereas the smooth and cardiac muscles are involuntary ones.</span>
Answer:
Concentration gradient
Explanation:
Concentration gradient of the ions across the membrane generates the membrane resting potential.
Concentration gradient means that there is unequal distribution of the ions on different sides of membrane. For example, the concentration of K ions is much higher within the cell then out of the cell. Opposite is with the Na ions. When ions move from the area of their higher concentration to the are with the lower concentration, we say they move down the gradient or diffuse (no energy required). On the other hand, movement of ions against their gradient means that this process requires energy and involves protein pumps.
