Question

A 70-year-old woman has a complex medical and a current drug regimen that includes calcium and vitamin D supplements for osteoporosis, metformin (Glucophage) for type 2 diabetes, phenelzine (Nardil) for depression, and metoprolol (Lopressor) and furosemide (Lasix) for hypertension. The woman is requesting dextromethorphan for the treatment of a recurrent cough. What component of her drug regimen contraindicates the use of dextromethorphan?

Answer 1

Answer:

Phenelzine (Nardil)

Explanation:

taking both together (Phenelzine and Dextromethorphan) can increase the risk of a condition called serotonin syndrome (confusion, hallucination, seizures, changes in blood pressure, increase heart rate, fever, excessive sweating, shivering, shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramp, nausea, vomiting, and diarrhea).  

Severe cases:  Coma or Death

https://www.drugs.com/drug-interactions/dextromethorphan-with-phenelzine-844-0-1839-0.html