Question

D. Now calculate resting Vm given the following relative permeability ratios. Assume that there is no meaningful permeability to Ca2+. (1pt) PK : PNa : PCl = 1.0 : 0.04 : 0.45 E. Let’s say that the K+ permeability increases, for example because of expression of more K+ channels. Calculate Vm with new the permeability values and discuss how the membrane potential has changed in relation to the potassium equilibrium potential EK. (roughly 1 sentence) (1pt)+

Answer 1

Answer:EX = RT ln [X]o

.........zF.....[X]i

EX = (1.987 cal/deg.mol)(293 deg) ln [X]o

.........z(23,062 cal/volt.mol)................[X]i

OR

EX = (8.315 joules/deg.mol)(293 deg) ln [X]o

.........z(96,485 joules/volt.mol)................[X]i

EK+ = 0.025 ln(12/400) = -0.088 V = -88 mV

ENa+ = 0.025 ln(450/55) = 0.053 V = 53 mV

ECa+2 = 0.0126 ln(10/0.0001) = 0.145 V = 145 mV

ECl- = -0.025 ln(550/56) = -0.058 V = -58 mV

Step-by-step explanation: