In modern times we do not have to worry about it thanks to the remarkable ... Smallpox has been identified as a possible agent of bioterrorism (1). .... In Europe, where the medical profession was relatively organized, the new .... In July 1796, Jenner inoculated the boy again, this time with matter from a fresh smallpox lesion.
Sweating is the body's way of trying to cool the body down, so his core temperature may have raised significantly or he is over-heating.
I would say the first and the last choices
Increased risk of coronary heart disease