Question

crescentus has a well described cell cycle. Based on your knowledge of the cell cycle, what would happen if the a mutation of the Ccrm gene ocurred causing the gene to be non-functional? What effect would it have on the cell cycle?

Answer 1

Answer:

Explanation:

Ccrm is a DNA methyl transferase. This enzyme helps in switching from fully methylated stated to hemimethylated state at its target motif. In this way this gene helps in expression of genes which helps in controlling the cell cycle progression.

When the Ccrm gene is found to be non functional in form. Then there is no switching occur from fully methylated to hemi methylated state at its target motifs. That's why there is not found expression of those genes which are involved in the cell cycle progression. In this way there is not found replication of DNA and there is not found replication of chromosome. That's why there is found single chromatid containing chromosome even after S phase. That's why the daughter cell will not get equal amount of genetic material. And cell cycle becomes futile.