Answer:
i hate getting questions like these
Explanation:
Answer:
A. 14.59
Explanation:
Firstly, rounding a number means making a number simpler but keeping its value close. So rounding 14.587020 means making it look less complex but making sure the rounded value is within range of the original value.
Next, we have to know that to round a number;
* Digits below 5 (<5) rounds down the next digit to their left i.e. we leave the digits the same and turn the rounding digit to 0.
* Digits above 5 (>5) rounds up the next digit to the left i.e. we add 1 to the next digit
Next, to round to 4 significant digits means we want to see only the first four non-zero digits in our value. Note that, all non-zero digits i.e. 1-9 are significant
Hence, 14.587020 will be:
= 14.587020
= 14.58700
= 14.59000
We have four (4) digits which are non-zero already, hence we stop here and remove all zeros to the right
Hence, 14.587020 to 4 significant digits is 14.59 i.e. 14.587020 ~ 14.59
Numerous antiepileptic medications, such phenytoin, have been designed to block voltage-gated sodium channels (VGSC) in neuronal membrane. In addition, multiple toxins and pharmacological modulators work by attaching to various biophysical states of the VGSC to cause their effects. Depending on how modulatory agents act, some VGSC states are stabilized or destabilized, altering the channel's biophysical properties. The first anticonvulsant to successfully treat epileptic disorders without causing undesirable side effects such as brain drowsiness was phenytoin.
Phenytoin has been indicated to block high-frequency neuronal activity potentials from the inner vestibule of the pore, as demonstrated by electrophysiological research and site-directed mutation.
Frequency and voltage both affect phenytoin binding.
There are theories that phenytoin interferes with the late sodium current that sustains depolarizations in epilepsy by blocking non-inactivated channels.
To learn more about phenytoin click here
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