Regulation Of Gene Expression.
A 3-base deletion in the AAUAAA sequence in the 3' untranslated region of an mRNA that eliminates the AAU, thereby preventing RNA polymerase from polyadenylation the mRNA would have the effect of; decreasing the number copies of the polyeptide that would be translated from this mRNA. A deletion is a mutation in which a part of a chromosome or a sequence of DNA is lost during DNA replication.
On his visit to the Galapagos Islands, Charles Darwin discovered several species of finches that varied from island to island, which helped him to develop his theory of natural selection.
Answer:
a. inhibits cAMP phosphodiesterase, the enzyme that converts cAMP to AMP.
Explanation:
The phosphodiesterases are a group of enzymes that are capable of breaking phosphodiester bonds such as those between nucleotides in nucleic acids. The Cyclic adenosine monophosphate (cAMP) is a second messenger involved in intracellular signaling pathways. This molecule (cAMP) is hydrolyzed by the cAMP-dependent phosphodiesterase, which catalyzes the enzymatic breakdown of phosphodiester bonds (i.e., hydrolyzing cAMP to 5-AMP). The cAMP levels are modulated by the balance between its generation and the degradation via cyclic nucleotide phosphodiesterase.
