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I believe it will be Africa.
These are used as Potentiate pain relief.
Medications that might possibly affect painful symptoms including opioid analgesics, anticonvulsants , tricyclic antidepressants, capsaicin, benzodiazepines and skeletal muscle relaxants were gradually withdrawn during the study‐washout period. Paracetamol was allowed as rescue medication.
Tricyclic antidepressants are the most common type of antidepressant used for pain. These antidepressants inhibit the reuptake of serotonin and norepinephrine at the synapse, but do so differentially according to chemical structure.
<h3>How Antidepressants Work in Pain Management?</h3>
The explicit way in which antidepressants are effective in pain management remains unknown, but multiple mechanisms are likely to be involved.
Perhaps the most popular theory is that antidepressants exert their effects on serotonin and norepinephrine, particularly along the descending spinal pain pathways. Antidepressants may also exert adjunctive therapeutic influences through histamine receptors as well as modulation of sodium channels.
To learn more about pain relieving drugs from the given link
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Differences between descriptive and analytical epidemiology
1. Descriptive epidemiology answers this questions who? what? where? when? Of the disease in an attempt to generate a hypothesis while analytical epidemiology is the studies that are conducted to test the hypothesis and give conclusions of a specific disease. Answers the questions why and how.
2. Descriptive epidemiology generates a hypothesis while analytical epidemiology tests the hypothesis.
3. Descriptive epidemiology identifies a group at a risk of a certain disease while analytical gives the cause of a disease.
4. No interventions are done in descriptive epidemiology while interventions are analyzed in analytical epidemiology
Similarities
1. They are both research design used in epidemiology.
2. Both study causes, the occurrence of a disease or health condition.
3. Outcomes from both aid in fulfilling epidemiology objectives.
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<span>The Coroner is an independent office holder with responsibility under the law for the medicolegal investigation of certain deaths. A Coroner must inquire into the circumstances of sudden, unexplained, violent and unnatural deaths. This may require a postmortem examination, sometimes followed by an inquest. Hope this helps:)</span>
