Fetal alcohol syndrome is a serious condition that arises due to the mother drinking alcohol during pregnancy. These conditions can harm each person in different ways and can range from mild to severe, with long-term implications that can include physical, mental, behavioral or learning problems. As for the abnormal facial characteristics, they present, for example, a less marked groove between the nose and the upper lip (this fold is called the filter or subnasal groove).
Pretty confident that it is A, judging by that the word composition is used as a combination or a ratio of 2 things. Also none of the other options make sense.