1.41×10⁷
because the decimal points move from 7 digits.
Answer:
By preventing the synthesis of DNA halting cell growth.
Explanation:
Fluorouracil and methotraxate prevent the synthesis of the neucleoside Thymidine thus preventing DNA replication and elongation. Methotraxate has a structure analogous to Folic acid which is important for thymidine synthesis. Thus, it acts as a competitive inhibitor on dihdrofolate reductase an enzyme that is essential for tetrahydrofolate formation, a folic acid derivative.
Fluorouracil acts by inhibiting thymidylate synthase which catalyses an essential step in Thymidine synthesis.
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