The statement is once the enzyme binds to the specific substrate molecule, structural changes can occur in the active site to accommodate the product.
I think mutation so D. If not then A
<span>The blood provides your body with the oxygen and nutrients it needs. It also carries away waste. Your heart is sort of like a pump, or two pumps in one. The right side of your heart receives blood from the body and pumps it to the lungs.</span>
Natural selection involve natural causes while artificial selection is by human breeding or human intervention.
The process of domestication is called artificial selection. Like natural selection, artificial selection acts by allowing differential reproductive success to individuals with different genetically determined traits in order to increase the frequency of desirable traits in the population. Natural selection and selective breeding can both cause changes in animals and plants. The difference between the two is that natural selection happens naturally, but selective breeding only occurs when humans intervene.