I believe that substance would be water.
Explanation:
Saliva contains special enzymes that help digest the starches in your food. An enzyme called amylase breaks down starches (complex carbohydrates) into sugars, which your body can more easily absorb. Saliva also contains an enzyme called lingual lipase, which breaks down fats.
There are many reasons to why slaves were essential in the colonial economy:
Slaves were generally used more in the south, because large plantations were found there, which meant that the need for large amounts of workers.
Slaves provided cheap labors, and as they were not "citizens" of the US, they were not allowed their rights.
Slaves were also relatively easy to buy and replace, however, their survival rates were not that good after they traveled long distance.
etc.
hope this helps