Answer:
There is growing evidence to indicate that age-related declines in growth hormone (GH), insulin-like growth factor (IGF)-1, and androgen and estrogen production play a role in the pathogenesis of sarcopenia (an age-related decline in muscle mass and quality). Although GH supplementation has been reported to increase lean body mass in elderly individuals, the high incidence of adverse effects combined with a very high cost has limited the applicability of this form of therapy. The assessment of an alternative approach to enhance the GH/IGF-1 axis in the elderly by using GH-releasing hormone and other secretagogues is currently under way and is showing some promise. Testosterone replacement therapy may increase muscle mass and strength and decrease body fat in hypogonadal elderly men. Long-term randomised, controlled trials are needed, however, to better define the risk-benefit ratio of this form of therapy before it can be recommended. Available data are currently insufficient to decide what role estrogen replacement therapy may play in the management of sarcopenia. Therefore, although the evidence linking age-related hormonal changes to the development of sarcopenia is rapidly growing, it is still too early to determine the clinical utility of hormonal supplementation in the management of sarcopenia.
Answer:
The correct answer is A. Brief stressors lead to changes in cytokine production.
Explanation:
Cytokines form an important group of proteins that act as mediators of communication between living cells. They can exert their action in a paracrine way (between neighboring cells within the same tissue), or endocrine (between cells located in different tissues). The imbalance on the immune system that stressful events exert is an increase in the production of pro-inflammatory cytokines and their associated spectrum of age-related syndromes and diseases. Proinflammatory cytokines are soluble mediators that promote and mediate inflammatory processes, the following stand out: interleukin 1 (IL-1) is involved in the regulation of the immune process and inflammation; interleukin 6 (IL-6) that also serves as a link between the endocrine system and the immune system; and Tumor Necrosis Factor (TNF), which has the ability to destroy certain cell lines and initiate the cascade of pro-inflammatory cytokines and other mediators.
Answer:
C. 100% of the offspring will be red-eyed and 100% of females will be carriers.
Explanation:
XR XR
Xr XRXr XRXr
Y XRY XRY
C) 100% of the offspring will be red-eyed, and 100% of the female offspring will be carriers.
This is false. DNA transcription is the first step in gene expression.
