I believe the answer is c) situational variables
The three themes in a modest proposal are Sincerity, Colonialism and Misanthropy.
Swift gave the idea of the modest proposal. A modest proposal refers to the idea which is not liked by everyone and is distasteful and unorthodox but had to be put forward as no other options are left. There are many themes in a modest proposal. Sincerity refers to the value of doing the work without any pressure with one's own will. It also refers to completing the work on time without any external force. Colonialism refers to the rule of a certain power over the group of people by controlling their life and all the supplies they require to lead a life. For example, The British setup colonies in different parts of the world and India was one of them. Misanthropy is a term that refers to the hatred of humankind.
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Colchicine is a drug that can prevent the formation of microtubules. By blocking the synthesis of spindle microtubules, it will stop mitosis in cell division.
A traditional anti-mitotic medication called colchicine prevents mitotic cells from dividing during metaphase. It forms tubulin-colchicine complexes with soluble tubulin in an imperfectly reversible way, which bind to the ends of microtubules to stop the elongation of the microtubule polymer.
Colchicine is an alkaloid from the Colchicum autumnale plant that prevents microtubule polymerization, which is thought to be necessary for collagen production. This substance is therefore thought to function as an antifibrotic substance by inhibiting collagen production and deposition.
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In the poem "A Valediction: Forbidding Mourning" by John Donne, the opposing terms are metaphorical. Donne is stating that their love is spiritual, not just physical. While the "laity" type of love is formed by people, the "priesthood" type is considered an unseen force. Laity love requires physical interaction, while priesthood love lasts beyond the human senses. The author states that because their love is spiritual, and they are one, when they separate they can only expand it.
He urges her to not cry because any sign of mourning will welcome outsiders to interrupt their love, and see his parture as temporary. Donne wrote this to express in faith in the long-distance relationship, and that she should not mourn him leaving.
