Liver- a vital organ only found in vertebrates which detoxifies various metabolites, synthesizes proteins and produces biochemicals necessary for digestion and growth. In humans, it is located in the right upper quadrant of the abdomen, below the diaphragm.
The structure that surrounds the cell membrane of some cells, giving the cell a rigid shape is the cell wall.
It would be the pubis bone.
Some of the core reasons are:
1) Deforestation
2) Excessive use of fossil fuels
3) Unevenness of Garbage
4) Increasing Population
5) Expansion of Urban area
Hope this helps!