Carbon has four available binding sites and depending on how one atom binds to other atoms, it can form different structures. If you look up the structure of diamond and graphite, you’ll see that they are all made out of carbon but they are arranged differently.
Temperature can cause an enzymes shape and function to alter due to the fact that once an enzyme reaches its optimum level, if it goes over it begins to denature. If the temperature is below optimum, then an enzyme will work at a slower rate. Also, the pH can affect an enzyme.