Paliperidone has low affinity
for lipid-rich environments compared from the parent compound risperidone. Due to
its hydrophilicity characteristic, paliperidone is capable of hydrogen bonding
with other molecules containing water and hydroxyl groups. Lipophilicity is a
determining factor for the rate and degree of metabolism of the drug in the
body and for crossing the blood–brain barrier (BBB).
Moreover, these differences are
implicated in synaptic plasticity and neuronal firing effects in the mechanism
of mitochondrial movement, protein expression, and phosphorylation of the drug.
Paliperidone as a mood stabilizer is an active metabolite of risperidone with antipsychotic effects used
for the treatment of schizophrenia and its associated disorders.
<span> </span>
Answer:
The scientific method
Explanation:
1. Observation
2. Ask a question
3. Form hypothesis
4. Make a prediction of hypothesis
5. Test Prediction
6. Iterate: make new hypothesis or problems with found results.
In the United States the direction the continental polar air mass move South toward the Gulf of Mexico to replace the rising maritime tropical air mass.
Answer: Option A
<u>Explanation:</u>
Air masses are large bodies of air moving horizontally in a very uniform way. Continental polar air mass is an air mass that forms near the poles. It originates in northern Canada and Alaska and move south then East.
The continental polar masses are the causes for the severe cold weather in the South during the cold months. Maritime tropical mass are warm and have high moisture content. During winter it comes in contact with the continental polar mass hence getting stabilized.
Answer: D. strata
Explanation:
I took a small quiz and it had this same question on it and the answer was strata
Hope this helps :)
