If nondisjunction occurs and an individual survives, which disorder can occur? Chromosomal mutations can have a variety of effects on individuals. Klinefelter syndrome is a genetic disorder that occurs when a male has an extra copy of the X chromosome.
Answer:
d) a polypeptide missing an amino acid.
Explanation:
Deletion is a type of mutation when one or more codons from the reading frame are removed. This results in the production of a relatively shorter mRNA that lacks one or more codons otherwise present in the non-mutated mRNA. When there is a deletion of a single codon in the gene for cystic fibrosis, the resultant shorter mRNA codes for a polypeptide chain that does not carry one amino acid. For example, deletion of one codon results in deletion of a Phe residue present at position 508 in CFTR. The mutated transmembrane protein CFTR folds in an improper way.
A C B
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