Answer:
Genetic diversity is important because it could ensure that certain groups of individuals, species, or populations will be able to adapt to certain environmental factors. Thus, genetic variation helps the species in terms of its adaptability, survival, and its evolution
Explanation:
Answer:
The CFTR behaves like a channel for chlorine. Its dysfunction affects both the transport of this ion and other ions and the transport of water, which causes a thickening of secretions, an alteration of mucociliary transport and local defenses, facilitating bacterial colonization and promoting the release of pro-inflammatory mediators in the airway
Explanation:
CFTR is a protein expressed in the epithelial cells of the respiratory system, pancreas, bile ducts, sweat glands and genitourinary system. It is made up of a single chain made up of 1,480 amino acids. It contains 12 hydrophobic regions embedded in the lipid membrane and acts as a channel for chlorine.The highest levels of expression of the CFTR protein are found in serous cells of the submucosal glands of the proximal airway. In them, Cl- is released to the outside. In addition, there are channels for Na +, through which this ion is also secreted in the same direction. These movements cause the displacement of water and also of mucins, originating in the submucosal glands, allowing their presence on the surface of the airway. For all this to occur normally, a basolateral Na + - K + - ATPase cotransporter must function, another basolateral cotransporter formed by Na +, K + and 2 Cl-, which allows the latter to enter the cell, and an apical CFTR channel through which it exits the Cl- of the cell towards the acinar lumen. Na + leaves the cell following Cl- by a paracellular pathway accompanied by water. When CFTR malfunctions, Cl- does not exit through this channel and this implies a decrease in Na + and water in the canalicular lumen, with the consequent thickening of secretions.
Answer:
Cytokines made by other innate cells, such as macrophages or dendritic cells
Explanation:
Innate Pattern Recognition Receptors (PRRs) on Dendritic cells and macrophages sense and respond to PAMPs and produce cytokines. Cytokines start the innate immune response.
The cytokines are produced in response to pathogen-associated molecular patterns (PAMPs) such as peptidoglycan monomers or CpG sequences on bacterial and viral genomes. Cytokines produced in response to pathogen receptors on cell surfaces, such as the inflammatory cytokines IL-1, IL-6, IL-8, and TNF-alpha, chemokines and type I interferons that act on leukocytes so as to promote and control early inflammatory responses.
Answer:
by cloning it with the latest technology that my parent bought me because im rich
