I believe a and b and possibly c and e. I’m not sure though, especially on e.
Answer:
Explanation:
The osmotic gradient in the kidney typically in the medulla is a process that generates urine that is 5 times more concentrated so as to reduce the loss of water from the body.
The countercurrent multiplication is a process that uses energy to produce the osmotic gradient in the kidney, this process facilitates the reabsorption of water from the tubular fluid. This mechanism moves the sodium chloride from the tubular fluid to the interstitial space of the kidneys. The osmotic gradient can be developed in two ways:
1. The single effect: This involves the transport of sodium chloride from the tubular fluid and moved to the ascending limb then finally to the interstitial fluid. As a result of this, the water moves passively down to the concentration gradient out of the tubular fluid than to the descending limb of the interstitial space, until the equilibrium is achieved.
2. Fluid flow method: The tubular fluid enters into the descending limb. This pushes the fluid into high osmolarity typically down the tube. This way the osmotic gradient develops.
Subsequent INR readings are influenced by the dose, method, and initial INR of vitamin K. For intravenous vitamin K doses of 2 mg or more, INR decrease is comparable. FFP preadministration has no effect on INR readings 48 hours or more after vitamin K administration.
What is Abstract of Vitamin K dosing to reverse warfarin based on INR, route of administration, and home warfarin dose in the acute/critical care setting?
- Commonly, vitamin K is used to reverse the anticoagulant effects of warfarin. The ideal vitamin K dosage and delivery method that does not lengthen bridging therapy are still unclear.
- To ascertain the elements affecting the level and pace of vitamin K-induced INR reversal in the acute/critical care setting.
- 400 patients' charts from between February 2008 and November 2010 who got vitamin K to counteract the effects of warfarin were examined. International normalized ratios (INRs), intravenous or oral vitamin K doses, and whether or not fresh frozen plasma (FFP) was administered were among the information gathered. INRs were measured 12, 24, and 48 hours before vitamin K treatment.
- At baseline, 12 hours, 24 hours, and 48 hours, respectively, intravenous vitamin K decreased INR more quickly than oral vitamin K (5.09, 1.91, 1.54, and 1.41 vs. 5.67, 2.90, 2.14, and 1.58). Subsequent INR values were impacted by baseline INR (p 0.001), method of administration (p 0.001), and vitamin K dosage (p 0.001). For intravenous vitamin K doses of 2 mg or more, there was a similar drop in INR. Home warfarin dose had no effect on INR responses to intravenous or oral vitamin K (p = 0.98 and 0.27, respectively). FFP had no effect on INR readings 48 hours later. Although larger vitamin K doses and longer anticoagulation bridge therapy appeared to be related, neither the incidence (p = 0.63) nor the duration (p = 0.61) were statistically significant.
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Answer: A-Antitussives
Explanation: Antitussives are cough suppressants. With a dry, non-productive cough you need to suppress it.