Answer:
E. Interleukin-1
Explanation:
Interleukin-1 is produced by macrophages and is involved in promoting the proliferation of helper T cells. Interleukin-1 also acts on the hypothalamus to cause fever. Fever refers to abnormally high body temperature. During infection and inflammation, the hypothalamic thermostat is reset in response to interleukin-1 resulting in fever. The presence of certain bacterial toxins in the body triggers the release of interleukin-1 from macrophages and the body temperature is elevated. Fever inhibits the growth of some microbes, intensifies the effects of interferons, and stimulates the body's immune reactions.
<span>The most crucial principle of ELISA (enzyme-linked immunosorbent assay) is a highly specific antibody-antigen interaction.</span>
ELISA is a biochemical technique used to detect the presence of an antibody or an antigen in the biological sample. Simply described, in an ELISA, an antigen is immobilized on a solid surface and then a specific antibody is applied over the surface so that it can bind to the antigen. The antibody is usually linked to an enzyme, and in the final step, a substrate for that enzyme is added. The enzyme can convert it to some detectable signal, most commonly a color change. <span>Medical usage of ELISA is in the diagnosis of HIV infection, pregnancy tests, measurement of cytokines…</span>
