Some molecules that are required by a cell are so large that they cannot pass into a cell by either the cell membrane or by any carrier protein. These molecules are transported into the cell by the process named as endocytosis.
In this process, the cell membrane forms a vesicle, a membrane-bound sac, around the large molecule. Then, the vesicle pinches the molecule into the cytoplasm of the cell. Energy is required for this process to occur.
Regional metamorphism takes place when rocks are buried deep in the crust. It is commonly associated with convergent plate boundaries and mountain range formation.
In other words<em><u> regional metamorphism takes place over wide areas and results from both pressure and temperature generated at convergent plate margins during subduction and continental collision.</u></em>
It results in deformation in non-hydrostatic and differential stress conditions and creates strongly foliated metamorphic rock (slates, schists, gneiss)
