1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Anna11 [10]
3 years ago
11

An experiment was performed to study the progress of cells through the mitotic cell cycle. The compounds listed below were used

individually to study their effects on the cell cycle. The cells on the left are examples of the cells at the beginning of the experiment. The cells at the right are representatives of three different experimental treatments using the compounds listed below. a. cytochalasin: b. an inhibitor of actin microfilament assembly colchicine: c. an inhibitor of microtubule formation aphidicolin: d. an inhibitor of DNA polymerase activity emetine: e. an inhibitor of ribosome activity (and therefore protein synthesis)
Biology
1 answer:
Hatshy [7]3 years ago
5 0
<h2>Mitotic Cell Cycle</h2>

Explanation:

a. Cytochalasin: an inhibitor of actin microfilament

  • Cytokinesis is the process by which cytoplasm is divided into two cells hence generation of two daughter cells
  • In animal cells the division of cytoplasm starts with the assembly of contractile ring
  • Contractile band consists of actin and myosin and catalyze cleavage furrow formation
  • Cytochalasin is a drug that blocks the polymerization of actin filament
  • When cytochalasin is added dividing cell fails to undergo in cytokinesis due to defective assembly of contractile band

b. Colchicine: an inhibitor of microtubule formation

  • Colchicine tightly binds with free tubulin dimer and prevents its polymerization
  • In this case mitotic spindle apparatus do not assemble and cells unable to do partitioning of chromosomes into two groups
  • Thus cell division is arrested

c. Aphidicolin: an inhibitor of DNA Polymerase activity

  • Aphidicolin is used to induce cell cycle arrest via specific inhibition of DNA Polymerase α
  • It blocks the cell cycle at early synthesis(S) phase

d. Emetine: an inhibitor of ribosome activity

  • It blocks the protein synthesis in eukaryotic cells by binding to small subunit(40 S) of ribosomes
  • It interferes with the synthesis and activities of DNA and RNA
You might be interested in
According to Selye (1956, 1974), which stage of reaction to stress stimulates the body to send messages from the hypothalamus to
Brums [2.3K]

Answer:

The alarm reaction stage

Explanation:

According to Selye, there are three stages of reaction to stress conditions. These are namely the alarm reaction stage, the resistance stage, and the exhaustion stage.

The alarm reaction stage is the first stage of stress reactions which includes perception of stress conditions. The hypothalamus sends signals to the associated glands and organs to prepare for the defensive responses.

The adrenal gland receives a signal to secrete the stress hormones while organs such as the liver are signaled to increase the glucose formation which in turn would serve as fuel during stress conditions.

7 0
3 years ago
The p53 gene is important to the cell cycle in G1 and G2, and cancer. What happens to the cell cycle when a mutation occurs in t
german

Answer:

PFFT this might help? sorry if not mate

Explanation:

Cell cycle checkpoint controls play a major role in preventing the development of cancer [see Sherr, 1994, for a more detailed discussion]. Major checkpoints occur at the G1 to S phase transition and at the G2 to M phase transitions. Cancer is a genetic disease that arises from defects in growth-promoting oncogenes and growth-suppressing tumor suppressor genes. The p53 tumor suppressor protein plays a role in both the G1/S phase and G2/M phase checkpoints. The mechanism for this activity at the G1/S phase checkpoint is well understood, but its mechanism of action at the G2/M phase checkpoint remains to be elucidated. The p53 protein is thought to prevent chromosomal replication specifically during the cell cycle if DNA damage is present. In addition, p53 can induce a type of programmed cell death, or apoptosis, under certain circumstances. The general goal of p53 appears to be the prevention of cell propagation if mutations are present. The p53 protein acts as a transcription factor by binding to certain specific genes and regulating their expression. One of these, WAF1 or Cip1, is activated by p53 and is an essential downstream mediator of p53-dependent G1/S phase checkpoint control. The function of p53 can be suppressed by another gene, MDM2, which is overexpressed in certain tumorigenic mouse cells and binds to p53 protein, thus inhibiting its transcriptional activation function. Other cellular proteins have been found to bind to p53, but the significance of the associations is not completely understood in all cases. The large number of human cancers in which the p53 gene is altered makes this gene a good candidate for cancer screening approaches.

5 0
3 years ago
Which of the following situation would a state government address
Alina [70]

Answer:

The power to lay and collect taxes

The Reagan administration tried to reduce the role played by the federal government in state and local matters

Resident/nonresidents

A republican form of government for every state

Extradition

State laws and court decisions must generally be honored by other states

Exercised simultaneously by the national and state governments

4 0
4 years ago
What is a rock and types of rocks<br>​
shutvik [7]
Dwayne Johnson, Also known a the Rock
5 0
3 years ago
Read 2 more answers
An exothermic reaction _____.
Fittoniya [83]
An exothermic action releases heat.
5 0
3 years ago
Other questions:
  • Which is part of the nonspecific immune response?
    8·1 answer
  • Compare lactic-acid fermentation and alcohol fermentation.​
    7·1 answer
  • Which of the following would describe Lamarck’s ideas about evolution?
    14·2 answers
  • The side of a mountain range that faces the wind often receives more ______ than the downwind side of the same range.
    8·1 answer
  • What are viruses considered to be non-living?
    14·2 answers
  • Which plant tissue transports sugars from the leaves of a plant back to the roots for storage
    13·1 answer
  • During photosynthesis, ___________ energy is converted into ____________ energy.
    15·1 answer
  • Sandstorms frequently happen in Mediterranean and tropical climates.
    10·2 answers
  • Anyone know this? cell cycle phases
    5·1 answer
  • What is carrageenan ?​
    7·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!