bottleneck effect --- > A disease wipes out almost 90% of a population of birds, but the species adapts, and after 5 years its numbers increase dramatically.
gene flow ---> A population of rats travels on a cargo ship and mate with rats in a new region.
founder effect ---> Biologists introduce a small population of lizards on an island as part of a conservation effort.
mutation ---> A change in a DNA sequence causes a lizard to develop a darker skin color, which helps it hide from predators.
The correct answer is the last statement.
If the regulatory serine is mutated to alanine, then acetyl-CoA carboxylase will get activated spontaneously and will produce malonyl-CoA. The increased concentrations of malonyl-CoA will obstruct the oxidation of fatty acids by preventing the entry of fatty acids into the mitochondria.
It is because the AMP-activated protein kinase phosphorylates the serine residues of acetyl-CoA carboxylase to inactivate it. If a mutation occurs in such residues, then the AMPL cannot phosphorylate acetyl-CoA carboxylase and this enzyme will get activated spontaneously.
In such a situation, there will be more than sufficient production of malonyl-CoA, which will inhibit the admittance of more fatty acid getting inside the mitochondria; this will indirectly prevent the oxidation of fatty acids.
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