Question

Many cancer drugs known as "antimitotics" target microtubules. what is the first stage of mitosis at which these drugs are likely to have an effect? bio

Answer 1

These antimitotics (i.e. taxanes) target microtubule proliferation. The stage of mitosis where it acts is at the M-phase, particularly in the metaphase. The phases of mitosis are prophase, metaphase, anaphase, and telophase. Microtubles first appear at the metaphase.