Which mutagens incorporate into dna and frequently pair with the wrong base?

1 answer:

3 0

Chemicals can make mutations by a number of mechanisms. Base analogs are incorporated into DNA and mostly pair with the wrong base. Alkylating agents, deaminating chemicals, hydroxylamine, and oxidative radicals change the structure of DNA bases, thus altering their pairing properties. Introducing agents wedge between the bases and cause single-base insertions and deletions in replication.

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