Hypophyseal portal system is a blood system of vessels in the microcirculation at the base of the brain, connecting the hypothalamus with the anterior pituitary. It is involved in quick transportation and exchange of hormones between the hypothalamus arcuate nucleus and the anterior pituitary gland. Hypothalamic-hypophyseal tract comprises of neurons that deliver vesicles with neurohormones from the hypothalamus to the posterior lobe of the pituitary gland. In this case, it is partly contained within the infundibulum (hollow stalk connecting the hypothalamus and the posterior pituitary gland).