Question

A child with cystic fibrosis has an altered protein in his cells that stops chloride ions from leaving the cells. This protein most likely affects the function of ?

Answer 1

The  altered  protein  affected  the  function   of  the  cell  membrane. The   cell  membrane which  contain  a  bilayer control  the  movement  of  substance   in  and  out  of  the  cell and organelles.  Due   to  this  it  is  selective  permeable  to ion  and  organic  molecules.

Answer 2

The right answer is chloride transport in cell membrane.

Cystic fibrosis is genetically translated by a mutation in the CFTR gene.

This gene encodes a transmembrane protein which is a chloride channel regulated by cAMP (cyclic Adenosine MonoPhosphate). This low-conductance channel is a regulator of other channels, particularly sodium channels such as the ENaC channel (Epithelial Na Channel) or the Outwardly Rectifying Chloride Channel (ORCC).