Unassembled or misfolded proteins in the RER can be damaging to the physiology of a cell and therefore are transported to the cy
tosol where they are degraded. This transport process is referred to asa. polyubiquitination.b. disulfide isomerization.c. dislocation.d. O-linked glycosylation.
Endoplasmic reticulum and the Golgi apparatus are the organelles where the post-translational modifications of proteins take place like folding of proteins.
Sometimes few proteins fail to fold properly and are a waste to the cell so has to de degraded. The misfolded proteins move from the endoplasmic reticulum to the cytosol through a process called "Protein dislocation".
Although the process is not properly misunderstood the protein degradation in the cytosol take place through deglycosylation and proteasomal ubiquitination.
