Answer:
B
Mutation is the ultimate source of genetic variation, but mechanisms such as sexual reproduction and genetic drift contribute to it as well Because prokaryotes are haploid, such a mutation immediately become part of the genetic makeup of the cell unlike eukaryotic diploids where a normal second copy of the gene usually protects the cell from the potentially lethal effect of such a mutation.
Http://www.pbs.org/wgbh/nova/cancer/folkman.html
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