Humans have a advantage over animals because humans have a working logic system, to explain this better, we can learn from things, while animals like bears, don't have much background knowledge on hunting us, just because they can't protect themselves from the multiple weapons we had. (Including early early humans)
for any unapproved drug to be used for human clinical studies, the physician who developed the drug must first submit an Investigational New Drug (IND) application to the FDA.
