On the flanks of the body, medial to the rectus femoris, the abdominal wall is composed of three layers. The external oblique muscles form the outermost layer, while the internal oblique muscles form the middle layer, and the transverses abdominus forms the innermost layer.
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
Answer:
The correct answer is option D.
Explanation:
The vasoconstriction or the narrowing of the blood vessels regulate the filtration rate of the glomerulus. The afferent arteriole vasoconstriction decreases the flow of blood to the glomerulus thus, decreases the filtration rate
The vasoconstriction of the efferent arteriole increases the glomerular filtration rate due to the increase in the blood level in the glomerular capillaries.
Thus, option D is the correct option.
Answer:
Liquid and Tablet,
For a liquid medicine you have to drink it, for a tablet medicine you have to drink it with water.
Liquid medicine example: Anthony throat was not feeling all right so he drank some medicine.
Tablet medicine example: Anthony had a headache so he took a tablet.
Explanation: