A parasite could determine the size of the population. Whether it grows or shrinks. It could also change genetics
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When air pollution began, it caused acid rain, damaging and destroying forests. It caused animals to become ill and potentially die as the acid rain ruined their environment. The air pollution also made around 400,000 people die faster than they would without air pollution.
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Unlike typical mammalian red blood cells, those from amphibians, such as frogs, contain a DNA-bearing nucleus that is visible in the center of the cell. The circulatory system of amphibians is rather unusual, their hearts having three chambers, two atria, and a single ventricle.
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The design of the amphibian circulatory system is curious because blood accumulates oxygen in the lungs and is then returned to the heart before being pumped into the rest of the circulatory system. Therefore, a mixing between oxygenated and deoxygenated blood occurs as blood returning to the heart from the lungs is mixed with incoming blood from the body. Frogs handle this situation by having a very slow metabolism and by absorbing some oxygen through their skin. In addition, the ventricle does have some directional control over the distribution of the blood.
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The presence of a nucleus in amphibian red blood cells allows researchers easy access to large quantities of amphibian DNA. Frog blood has both a solid and a liquid portion. The liquid plasma carries solid elements such as red and white blood cells. Blood can be collected from frogs and the red blood cells isolated by centrifugation. After removal of the residual plasma, purified cells can be treated with specific enzymes and detergents to digest the cellular envelope and release DNA from its protein complex. The DNA is then useful for scientific studies and experiments.
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The phrase "disease is an agent of natural selection" means that those individuals which carry specific genes to resist the disease will be selected by the nature, whereas those individuals which that don't have or not capable of developing resistance genes will be excluded.
It is a well-established fact that diseases (mainly outbreaks) are best action of nature to select only those individuals which can modify there genetic material and thrive against the changing environmental conditions. Let's take the example of Coronavirus outbreak (COVID-19) this year. From the statistics we know that old people that develop the disease are most likely killed within a few days. However, young people can develop immunity against the virus easily. Hence, nature selects young people and exclude older people. This natural phenomenon is however driven by the disease.