Answer and Explanation:
Ergotamine has been used for over 50 years and was the first specific drug to treat migraine attacks. Its therapeutic effect is due in part to its ability to contract the vessels. It is a vasoconstricting alkaloid used in migraine attacks, when treatment with non-steroidal anti-inflammatory drugs has no effect.
The mechanism of action of ergotamine is complex. The molecule has structural similarities to neurotransmitters such as seratonin, dopamine and adrenaline, and can therefore bind to various receptors and function as an inhibitor. Its use in the treatment of migraines is due to its vasoconstrictor effect of extracerebral intracranial blood vessels through their binding to the 5-HT1B receptor and inhibition of neurotransmitter binding.
Overuse of ergotamine may cause nausea, vomiting (to direct effects on the Central Nervous System in the vomiting centers) , malaise, headache, constriction of peripheral vessels and more severe effects such as ischemia of the extremities.
Ergotamine poisoning is called ergotism.
Ergotamine should not be used in patients with peripheral arterial or venous vascular insufficiency, ischemic heart disease, cerebrovascular disease, systemic infection and hypertension without effective control.
A-Tuberculosis is considered a chronic disease.
-Seth
This, the least common type of ADHD, is characterized by impulsive and hyperactive behaviors without inattention and distractibility. ADHD, inattentive and distractible type. This type of ADHD is characterized predominately by inattention and distractibility without hyperactivity.
Answer:
The correct answer to the following question will be "True".
Explanation:
- NIH (National Institutes of Health) is the world's largest public funding agency for biomedical research, investing more than $30 billion in taxpayer money to accomplish its mission of improving health, prolonging life, and reducing disease and disability.
- By fulfilling this goal, NIH promotes health by encouraging prevention and treatment, contributes to society through increased economic development and efficiency, and extends the knowledge base of bio-medicine by supporting cutting-edge science and nurturing today's and tomorrow's biomedical labor force.
Therefore, the given statement is True.
