An inhibitor of carbonic anhydrase would interfere with oxygen binding to hemoglobin, increase blood pH due to increased H+, increase the amount of bicarbonate formed in the blood and decrease the amount of carbon dioxide dissolved in plasma.
Carbonic anhydrase catalyses the reaction between carbon dioxide and water to form carbonic acid. Carbonic acid dissociates to form hydrogen carbonate ions and hydrogen ions. The hydrogen ions combine with haemoglobin to form weak haemoglobinic acid.
