Answer:
Oxygen or Minerals or Sugars (Oxygen is the most relevant one)
Explanation:
To survive, every cell must have a constant supply of vital substances such as sugar, minerals, and oxygen, and dispose of waste products, all carried back and forth by the blood cells. Without these substances, cells would die in a very short period of time.
It would not survie as long
thymine
adenine
cytosine
guanine
Explanation:
uracil is not because uracil is only RNA.
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Megacity would probably have the biggest affect on the immediate environment and possible the outlands of the megacity as well.