Genetic
since we are made from our dna
Proteostasis is mediated by chaperone proteins and protease systems, together with cellular clearance mechanisms such as autophagy and lysosomal degradation.
Chaperone proteins control assembly and inaccurate folding by binding to and stabilizing partly or completely unfolded protein polypeptides till the polypeptide chain is completely synthesized. Chaperone proteins also confirm the stability of unfolded polypeptide chains as they are being translocated into the subcellular organelles.
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The mantle is a layer inside a planetary bodybounded below by a core and above by a crust. Mantles are either made of rock or ices, and are generally the largest and most massive layer of the planetary body. Mantles are characteristic of planetary bodies that have undergone differentiation by density. The mantle is bounded on the bottom by the planetary core and on top by the crust. In addition to the Earth, the other terrestrial planets, a number of asteroids, and moonshave mantles.
