I believe it was the 15th century
By the early 1900s, Germany had worsening relations with all of the following except "Austria-Hungary", since a wave of nationalism in Germany gave them the impression that Austria-Hungary was really a part of Germany anyway.
Hysteria, on time of Sigmund Freud (Victorian Era) was a term coined for what today is called 'anxiety'. The fear or apprehension on what may happen next. Bill became blind without proper reason, in today's case, this is called Conversion Disorder. To treat, Bill must treat the source of anxiety first thru series of therapies.
1884 – Mary Agnes Snively, the first Ontario nurse trained according to the principles of Florence Nightingale, assumes the position of Lady Superintendent of the Toronto General Hospital's School of Nursing.
Between 1880 and 1900, cities in the United States grew at a dramatic rate. Owing most of their population growth to the expansion of industry, U.S. cities grew by about 15 million people in the two decades before 1900. Many of those who helped account for the population growth of cities were immigrants arriving from around the world. A steady stream of people from rural America also migrated to the cities during this period. Between 1880 and 1890, almost 40 percent of the townships in the United States lost population because of migration.
