When cells communicate by the signaling process, one cell produces a signaling molecule that must be received by the signal receptor on or in the responding cell. Signaling molecules are often called ligands, a general term for molecules that bind specifically to other molecules (such as receptors).
Answer: Chromosomes become visible, crossing-over occurs, the nucleolus disappears, the meiotic spindle forms, and the nuclear envelope disappears. ... At the start of prophase I, the chromosomes have already duplicated. During prophase I, they coil and become shorter and thicker and visible under the light microscope.