Changes in chromosome include deletions, duplications, inversions, and translocations.
Deletion occurs when an end of a chromosome breaks off.
Duplication is the presence of a chromosome segment more than once in the same chromosome.
Translocation is when a fragment of chromosomal breakage join a nonhomologous chromosome.
Reciprocal translocation is a chromosome abnormality caused by exchange of parts between non-homologous chromosomes.
Robertsonian translocation occurs when two non-homologous chromosomes get attached, meaning that given two healthy pairs of chromosomes, one of each pair "sticks" together.