Death from diseases, lack of food, like each other.
An effect of the discovery of the New World in the late fifteenth century was a global exchange of plant life as different plants were transported to America where they thriwed, but different plants were also transported back to Europe and thriwed there as well.
He brought them a treaty, The Meiji restoration happened and because of that the Tokugawa Shogunate ended. And modernization of japan started to begin.
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