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bulgar [2K]
4 years ago
14

In humans, the hormone testosterone enters cells and binds to specific proteins, which in turn bind to specific sites on the cel

ls' DNA. These proteins probably act to do what?
Biology
1 answer:
Crank4 years ago
4 0

Answer:

They act to regulate the expression of specific genes (androgen-responsive)

Explanation:

Testosterone is a reproductive hormone in male humans. Testosterone as well as its closely related hormones e.g dihydrotestosterone, all belong to a class of hormones called "Androgens".

Androgens operate by entering into a cell and binds with specific androgen-receptor proteins (AR proteins). This contact activates the AR proteins, forming an androgen-receptor complex.

This complex then translocates into the nucleus of specific cells to bind to the DNA. Once it binds, it either inhibits or promotes the expression of specific genes (androgen-responsive). Hence, AR proteins are transcription factors because they play a significant role in regulating transcription of specific genes i.e. turning 'on' or 'off' of specific genes.

This process helps to direct the development of male sexual characteristics.

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3 years ago
Most black bears (Ursus americanus) are black or brown in color. However, occasional white bears of this species appear in some
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Answer and Explanation:

<em><u>The number of observed individuals</u></em>:

  • AA 42
  • AG 24
  • GG 21

<u><em>Total number of individuals, N</em></u>= 87 = 42 + 24 + 21

<u><em>Allelic frequencies</em></u>:

  • f(p) = (2 x AA + AG)/ 2 x N

       f (p)= (2 x 42 + 24) /2 x 87

       f (p) = (84 + 24) / 174

       f (p)= 108 / 174

      f (p) = 0.62

  • f (q) = (2 x GG + AG)/2 x N

        f (q) = (2 x 21 + 24 )/2 x 87

        f (q) = (42 + 24)/ 174

        f (q) = 66/174

        f (q) = 0.38

p + q = 1

0.62 + 0.38 = 1

<em><u>The expected genotypic frequency:</u></em>

  • F (AA)= 0.62 ² = 0.3844
  • F (AG) = 2 x A x G = 2 x 0.62 x 0.38 = 0.4712
  • F (GG) = 0.38 ² = 0.1444

AA + AG + GG = 0.3844 + 0.4712 + 0.1444 = 1

<u><em>The number of expected individuals</em></u>:

AA= (0.62)² x 87 = 0.3844 x 87 = 33.44

AG= (0.4712) x 87 = 40.99

GG= (0.38)² x 87 = 12.563

<u><em>Total number of expected individuals</em></u> = 33.44 + 40.99 + 12.563 = 87

<u><em>Chi square</em></u>= sum (O-E)²/E

  • AA= (O-E)² /E

        AA=(42 - 33.44) ² / 33.44

        AA= 2.2

  • AB= (O-E)² /E      

        AB= (24 - 40.99)²/ 40.99

        AB=7.04

  • BB=(O-E)² /E

        BB= (21-12.563)²/12.563

        BB= 5.66

<u><em>Chi square</em></u>= sum ((O-E)²/E) = 2.2 + 7.04 + 5.66 = 14.9

<u><em>Degrees of freedom</em></u> = genotypes - alleles = 3 - 1 = 2

p value less than 0.05

There is enough evidence to reject the nule hypothesis. The genotype frequencies are not in equilibrium.

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