For use in (aerobic) respiration, polypeptides would first be hydrolysed to their amino acid monomers. These are each deaminated, i.e. have their amino groups removed, producing an organic acid, which can be fed into the Kreb's Cycle, and a waste product, ammonia (NH₃), which is moved to the liver and removed from the blood.
I personally think that video games are not a problem in a normal ‘teenagers’ life but if their parents or guardians are not being responsible it can cause some
Problems however for someone adults who put video games before a job or a relationship that’s 100% a problem so in conclusion you need to be responsible doesn’t matter if your a kid or a adult don’t let video games control your life or your health
The answer is to produce wood and paper products :)
Answer:
1. P120 is degraded in the 26S proteasome
2. The 26S proteasome has a major role in protein degradation and is critical for protein homeostasis
3. Cell cycle and DNA replication are cellular processes regulated by the Ras and NFkB pathways
Explanation:
The proliferation-associated nucleolar protein (p120) is a protein known to be expressed during the interphase of the cell cycle, specifically in G1 and early S phase, where any problem with DNA replication trigger a checkpoint, i.e., a molecular cascade of signaling events that suspend DNA replication until the problem is resolved. In mammalian cells, the 26S proteasome is responsible for catalyzing protein degradation of about 80% (or even more) of their proteins. The 26S proteasome acts to degrade rapidly misfolded and regulatory proteins involved in the cell cycle, thereby having a major role in protein homeostasis and in the control of cellular processes. It is for that reason that inhibitors that block 26S proteasome function have shown to be useful as therapeutic agents in diseases associated with the failure of protein degradation mechanisms (e.g., multiple myeloma). The NF-κB are highly conserved transcription factors capable of regulating different cellular processes including, among others, cellular growth, inflammatory responses and apoptosis. Moreover, the MAPK/ERK pathway is able to transduce different signals received on the cell surface to the nucleus. The MAPK/ERK pathway is activated when a singling molecule binds to a cell receptor which triggers a signaling cascade that ends when a transcription factor induces the expression of target genes, ultimately producing a response in the cell (for example, the progression through the cell cycle).
