Answer:
I believe "B"
Explanation:
In the Sun, the flows of hot plasma in the convection zone create the solar magnetic field. This is sustained by nuclear fusion in the Sun. ... The number of sunspots on the sun increase and decrease over time in a regular, approximately 11-year cycle, which is, in fact the solar magnetic activity cycle.
Answer:
Juvenile rheumatoid arthritis
Explanation:
Arthritis is a term used to refer a group of diseases that affects the joints such as knees, wrists and fingers.
Juvenile rheumatoid Arthritis is an autoimmune disorder that affects children which means the body attacks itself by mistakenly identifying its own cells as foreign .
The cause of this response is not yet known.
Some of the symptoms of the disease include stiffness, pain, joint swelling, skin rush, fever, slowed growth and fatigue.
It has no cure but in some cases children seem to outgrow the disease.
Human monoclonal antibody (mAbs) are emerging in the field of cancer therapy and have become an increasing proportion of new drugs that are recently approved. Although there are some methods to obtain antigen-specific mAbs from human B cells, it is generally impossible to directly immunize human beings with antigens of interest. For example, for infectious agents, those approaches are largely restricted. To solve these obstacles, two main approaches have been developed; either by humanizing antigen-specific antibodies from small experimental animals (which is laborious due to the great genetic differences from humans) or rely on the in vitro selection of antigen-specific binders from human antibody repertoires. However, the human mAbs developed by these methods are usually with low affinity.
We are now coming up with a much better idea that is humanizing non-human primates mAbs instead of murine mAbs. Due to the close genetic relationship with humans, immunized NHPs have more potential to be isolated with high affinity antibody to human target than other experimental species, such as mouse, rat and rabbit. In addition, with appropriate method, NHP antibodies are much<span> easier to be humanized</span> without any loss of affinity compared to widely used murine antibodies.
Resource: http://www.creative-biolabs.com/High-Affi-TM-Human-Antibody-Discovery.html
The official term is a megaflash :)
