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Answer and Explanation: In enzyme kinetics, one constant describing enzyme activity is <em>Maximal Velocity</em> (Vmax). It indicates how fast an enzyme can catalyze the reaction. It is dependent on substrate concentration.
As the muscle is an organ which needs a great amount of energy, the enzyme glycogen phosphorilase is very active on the organ, compared to the liver, where glicose is stored. So, the Vmax of glycogen phosphorylase expressed in muscle is faster than when expressed in the liver, means the enzyme in muscle has a bigger concentration of substrate and therefore will reach Vmax faster, i.e. will be significantly larger.
Katie has a rare neurological disease in which her neurons can receive new information and process it, but some of them just cannot pass the information along. This disease most likely affects the axon of the neurons. Since axon is the signal transmitting end of the neuron, if the fusion of the vesicles containing the neurotransmitters with the cell membrane around the synaptic cleft is hampered, then the signal transmission gets disrupted.